Numerical Study of Droplet Generation Process in a Microfluidic Flow Focusing

نویسندگان

  • Ali Lashkaripour Department of Life Science Engineering, University of Tehran, Tehran, Iran
چکیده مقاله:

Microfluidic flow focusing devices have been utilized for droplet generation on account of its superior control over droplet size. Droplet based microfluidics addressed many scientific issues by providing a novel technological platform for applications such as biology, pharmaceutical industry, biomedical studies and drug delivery. This study numerically investigated the droplet generation process of an aqueous flow in oleic acid oil in a microfluidic flow focusing device. A conservative level set method is conducted to numerically model the droplet generation process. The post processing of the simulation results are done using Canny edge detection image processing method, which is a novel approach. Moreover, the results of the numerical simulation were compared to the experimental data provided by Ten et al. on the same device. This method showed a maximum average deviation from the experimental results of 14.6% and a minimum of 6.96%. Also, by means of altering water and oil flows, the influence of parameters affecting droplet size, which lead to a better understanding of droplet generation phenomenon, was investigated in this study. Therefore, it can be concluded that the flow ratio and capillary number are the two primary parameters that affect droplet size, while capillary number showed more dominance in comparison to flow ratio.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

numerical study of droplet generation process in a microfluidic flow focusing

microfluidic flow focusing devices have been utilized for droplet generation on account of its superior control over droplet size. droplet based microfluidics addressed many scientific issues by providing a novel technological platform for applications such as biology, pharmaceutical industry, biomedical studies and drug delivery. this study numerically investigated the droplet generation proce...

متن کامل

Numerical Study of the Controlled Droplet Breakup by Electric Fields inside a Microfluidic Flow-focusing Device

Droplet-based microfluidics has received extensive research interests due to its superior control over the fluid flow. Conventional passive microfluidic flow-focusing devices confront difficulties in controlling droplet sizes in dripping regime especially when the dispersed phase has a large viscosity. External electric fields have been reported as an effective tool to manipulate droplet breaku...

متن کامل

Monodispersed microfluidic droplet generation by shear focusing microfluidic device

A microfluidic device designed to generate monodispersed picoliter to femtoliter sized droplet emulsions at controlled rates is presented. This PDMS microfabricated device utilizes the geometry of the channel junctions in addition to the flow rates to control the droplet sizes. An expanding nozzle is used to control the breakup location of the droplet generation process. The droplet breakup occ...

متن کامل

Negative Pressure Induced Droplet Generation in a Microfluidic Flow-Focusing Device.

We introduce an effective method to actively induce droplet generation using negative pressure. Droplets can be generated on demand using a series of periodic negative pressure pulses. Fluidic network models were developed using the analogy to electric networks to relate the pressure conditions for different flow regimes. Experimental results show that the droplet volume is correlated to the pr...

متن کامل

Droplet Generation in Flow-Focusing Microfluidic Devices for the Creation of Artificial Cells

This paper systematically investigated the effect of flow rate ratios between the water and oil phases, and concentrations of sodium alginate within the water phase, on the generation of droplets and capsules in a microfluidic reactor in order to facilitate artificial cell production within the water phase for biological experiments. Artificial cells, which simulate the processes that occur wit...

متن کامل

Flow Focusing in Microfluidic Devices

This paper presents numerical analysis of the hydrodynamic flow focusing in rectangular microchannels. The low Reynolds number pressure driven flow in symmetric system of crossed channels with three inlets and one outlet is investigated. The numerical model is used to elucidate the origin of broadening of the focused flow sheet observed experimentally close to the side walls of the outlet chann...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


عنوان ژورنال

دوره 46  شماره 2

صفحات  167- 175

تاریخ انتشار 2015-07-01

با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023